E
Barinthus Biotherapeutics plc BRNS
$0.63 -$0.01-1.39% NASDAQ
Recommendation
Dividend Power Score
Prev Close
Volume
Avg Vol (90D)
Market Cap
Dividend & Yield
--
52-Week Range
P/E (TTM)
--
EPS (TTM)

Company Overview

Barinthus Biotherapeutics plc is a clinical-stage biotechnology company focused on the discovery and development of novel immunotherapies that harness the human immune system to treat cancer and certain infectious diseases. The company operates within the biotechnology and biopharmaceutical industries, with a primary emphasis on T cell–based therapeutic platforms designed to induce potent and durable immune responses. Barinthus does not currently market approved products; its activities are centered on research, clinical development, and strategic collaborations.

The company’s core value proposition lies in its proprietary T cell immunotherapy platforms, which are designed to generate high-avidity CD8 and CD4 T cell responses against disease-specific targets. Formerly known as Scancell Holdings plc, the company rebranded as Barinthus Biotherapeutics plc to reflect its broader ambition to develop immune-modulating therapies beyond oncology. Founded in 1997, the company has evolved from an academic spin-out into a publicly listed, clinical-stage biotechnology firm with multiple programs in development.

Business Operations

Barinthus Biotherapeutics conducts its operations primarily through its wholly owned subsidiary, Scancell Limited, which houses its research, development, and clinical activities. The company’s business is organized around proprietary immunotherapy platforms, including SCIB and Modi-1, which are designed to stimulate targeted T cell responses against tumor-associated antigens. These platforms underpin its oncology pipeline, with candidates in clinical trials for indications such as melanoma and other solid tumors.

The company generates revenue primarily from research grants, tax credits, and, where applicable, collaboration or licensing income rather than from product sales. Operations are primarily based in the United Kingdom, with clinical trials conducted in collaboration with hospitals and research centers. As a clinical-stage company, Barinthus retains intellectual property rights to its core technologies and manages development internally, supplemented by contract research organizations and academic partnerships.

Strategic Position & Investments

Strategically, Barinthus Biotherapeutics is focused on advancing its lead immunotherapy candidates through clinical development while preserving optionality for future partnerships or licensing transactions. Growth initiatives center on expanding clinical data for its lead assets, broadening the application of its T cell platforms, and exploring combination approaches with other immuno-oncology agents. The company has historically emphasized capital efficiency and non-dilutive funding where possible.

Barinthus has not disclosed a large portfolio of subsidiaries or diversified investments; instead, it maintains a focused pipeline strategy. Its primary investments are directed toward clinical trials, manufacturing development, and intellectual property protection. The company is also involved in emerging areas of immunotherapy research, including the targeting of post-translationally modified antigens, which it believes may offer differentiation versus existing immuno-oncology approaches.

Geographic Footprint

Barinthus Biotherapeutics is headquartered in the United Kingdom, with its principal offices and laboratories located in Nottingham, England. This location anchors its research and development activities and reflects its origins as a UK-based academic spin-out. The company’s corporate structure and primary operating subsidiary are UK-based.

Internationally, Barinthus has an operational footprint through clinical trial activity and capital markets access rather than physical offices. Its securities are traded in the United States through a Nasdaq listing, providing access to U.S. investors and the global biotechnology investment community. Clinical development activities extend across Europe and may include sites in North America, depending on trial design and regulatory strategy.

Leadership & Governance

Barinthus Biotherapeutics is led by a management team with scientific and operational experience in immunology and biotechnology. The company’s leadership emphasizes rigorous science, disciplined capital allocation, and the translation of academic innovation into clinically meaningful therapies. Governance follows UK public company standards, with oversight from a board comprising executive and non-executive directors.

Key executives include:

  • Lindy DurrantChief Executive Officer
  • Lindy DurrantFounder and Chief Scientific Officer
  • Melanie ToyneChief Financial Officer
  • David GloverNon-Executive Chairman

The leadership team’s strategic vision centers on advancing differentiated immunotherapies through clinical validation while positioning the company for potential strategic partnerships or later-stage development opportunities.

Data complied by narrative technology. May contain errors

Top Tech Stocks
See All »
B
NVDA NASDAQ $178.56
B
AAPL NASDAQ $248.96
B
MSFT NASDAQ $389.02
Top Consumer Staple Stocks
See All »
B
WMT NASDAQ $121.09
B
Top Financial Stocks
See All »
B
B
JPM NYSE $287.97
B
V NYSE $299.71
Top Energy Stocks
See All »
B
ENB.TO TSX $73.47
B
ENB NYSE $54.07
Top Health Care Stocks
See All »
B
LLY NYSE $917.50
B
JNJ NYSE $237.60
B
AMGN NASDAQ $349.92
Top Real Estate Stocks
See All »
B
PLD NYSE $131.09