Signal Advance, Inc. engages in the engineering research and technology development business. It offers Signal Advance (SA) technology that modulates analog signals and reduces signal detection delays associated with various physical sensors, as well as reduction in response time, which includes improved performance in control, intervention, and signal transmission systems. The company also develops Analog Guard which is applied to analog encryption. It serves biomedicine, transportation, defense, communications, cyber-security, and industrial control systems. The company was formerly known as Biodyne Development Company, Inc and changed its name to Signal Advance, Inc. in 2007. The company was incorporated in 1992 and is based in Rosharon, Texas.